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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC27
All Species:
31.82
Human Site:
S154
Identified Species:
58.33
UniProt:
P30260
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30260
NP_001107563.1
824
91867
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Chimpanzee
Pan troglodytes
XP_511624
824
91839
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001115994
824
91959
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Dog
Lupus familis
XP_548047
825
91842
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_663411
825
91824
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Rat
Rattus norvegicus
NP_001019964
824
91645
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520967
385
43892
Chicken
Gallus gallus
NP_001006331
833
92606
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Frog
Xenopus laevis
NP_001085568
833
92363
S154
F
L
W
S
P
F
E
S
L
C
E
I
G
E
K
Zebra Danio
Brachydanio rerio
NP_958857
790
87878
E153
P
F
L
W
S
P
F
E
S
L
C
Q
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648093
900
101266
D153
F
M
W
H
A
F
A
D
L
C
L
L
G
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786824
824
91473
A152
P
E
K
T
F
H
F
A
S
T
P
T
V
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38042
758
85418
L121
Q
G
V
N
E
A
I
L
T
L
L
S
I
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.3
99.1
N.A.
96.9
97.4
N.A.
43.6
94.5
89.6
76.5
N.A.
39.2
N.A.
N.A.
49.2
Protein Similarity:
100
99.8
97.2
99.2
N.A.
98.6
98.5
N.A.
45.2
96.6
94.5
84.3
N.A.
57.4
N.A.
N.A.
67.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
0
N.A.
40
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
6.6
N.A.
60
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
70
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
8
0
0
8
0
62
8
0
0
62
0
0
62
8
% E
% Phe:
70
8
0
0
8
70
16
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
70
8
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
62
16
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
62
% K
% Leu:
0
62
8
0
0
0
0
8
70
16
16
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
16
0
0
0
62
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
62
8
0
0
62
16
0
0
8
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
8
0
8
0
8
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
70
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _